Saturated Synthetic Lecithins in Vdrl and Kolmer Antigens for the Sero-Diagnosis of Syphilis
نویسندگان
چکیده
منابع مشابه
Saturated synthetic lecithins in VDRL and Kolmer antigens for the sero-diagnosis of syphilis.
When pure individual synthetic lecithins became available for study (Baer and Kates, 1949, 1950), there was immediate interest in their possible use in cardiolipin antigens as substitutes for Pangborn lecithin. Rosenberg (1949) reported briefly on synthetic L-c-(dipalmitoyl)-lecithin in antigens for the Hinton, Kline, Rein-Bossack, VDRL, and Kolmer tests. He found that replacement of Pangborn's...
متن کاملSYNTHETIC L-oc-DIOLEYL LECITHIN IN ANTIGENS FOR THE SERO-DIAGNOSIS OF SYPHILIS: COMPARISON WITH OTHER LECITHINS*t
The lecithin which is used in cardiolipin antigens for the sero-diagnosis of syphilis is extracted from beef heart tissue or egg yolk by the methods of Pangborn, Maltaner, Tompkins, Beecher, Thompson, and Flynn (1951). The product is actually a mixture of individual lecithins containing chiefly unsaturated but also some saturated fatty acids, the composition varying with the source and method o...
متن کاملUse of an Individual Unsaturated Lecithin from Yeast in Antigens for The
Hanahan and Jayko (1952) isolated a pure individual unsaturated lecithin, L-ox-(dipalmitoleyI)lecithin, from fresh baker's yeast by adsorption on alumina. They showed that hydrogenation of this material produced the corresponding saturated lecithin which was identical with the synthetic L-oc-(dipalmitoyl)-lecithin of Baer and Maurukas (1952). The latter compound, when used in combination with c...
متن کاملUse of an individual unsaturated lecithin from yeast in antigens for the sero-diagnosis of syphilis.
Hanahan and Jayko (1952) isolated a pure individual unsaturated lecithin, L-ox-(dipalmitoleyI)lecithin, from fresh baker's yeast by adsorption on alumina. They showed that hydrogenation of this material produced the corresponding saturated lecithin which was identical with the synthetic L-oc-(dipalmitoyl)-lecithin of Baer and Maurukas (1952). The latter compound, when used in combination with c...
متن کاملSerological, nephelometrical, and statistical studies on the employment of synthetic lecithin in cardiolipin antigens.
Cardiolipin antigens, used in the sero-diagnosis of syphilis, are mixtures of the phospholipids, cardiolipin, and purified natural lecithin (beefheart or egg), and usually also contain cholesterol. In 1949 Baer and Kates (1949, 1950) succeeded in the synthesis of L-ac-dimyristoyl lecithin and in the following years other types of synthetic lecithin were produced, including a D-oc-dimyristoyl le...
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ژورنال
عنوان ژورنال: Sexually Transmitted Infections
سال: 1957
ISSN: 1368-4973
DOI: 10.1136/sti.33.4.249